
Roberta Madej, PhD, QTMB, Scotland UK & Deborah Payne, PhD, American Pathology Partners/UniPath, Denver, CO
Molecular Methods for Infectious Diseases. Linnea Baudhuin, PhD, Mayo Clinic, Rochester, MNĭescribes different modes of inheritance for single gene disorders, defines important molecular genetics terminology, describes types of genetic variants and discuss non-Mendelian patters of inheritance. Next Generation Sequencing and BioinformaticsĬhristina Lockwood, PhD, University of Washington, Seattle, WAĭiscusses the advantages of NGS, steps in NGS methodology, and summarizes different types of NGS assays. Lists sample requirements, names methods to isolate the DNA, and discusses the general principles of Southern blotting, PCR, and signal amplification.Įxplains different sample types used for nucleic acid testing, discusses DNA and RNA isolation and measurement techniques, describes the basics of gel electrophoresis of nucleic acids, the principles of the polymerase chain reaction and other nucleid acid amplification methods, as well as signal amplification and real time PCR. John Greg Howe, PhD, DABCC, Yale University School of Medicine, New Haven, CT
Each course can be completed online in approximately 1-2 hours and contains a lecture, readings, resources, and a quiz. This program is composed of nine courses, listed below. This program was developed to present the essentials of molecular pathology and provide laboratorians with an understanding of nine different areas of study. Developed with all levels of laboratory professionals in mind, the content of this program is at the basic to intermediate level and will provide participants with opportunities to increase their knowledge of diagnostic applications of molecular pathology.